Description
COMPOSITION:
Sevelamer Carbonate Tablets 400 mg & 800 mg
MODE OF ACTION:
Sevelamer (a polymeric compound) binds phosphate within the intestinal lumen, limiting absorption and decreasing serum phosphate concentrations without altering calcium, aluminum, or bicarbonate concentrations.
INDICATIONS:
In Hyperphosphatemia with CKD.
DOSAGE:
Control of serum phosphorous: Patients not taking a phosphate binder: 800-1600 mg 3 times/day with meals; the initial dose may be based on serum phosphorous levels: >5.5 mg/dL to <7.5 mg/dL: 800 mg 3 times/day, ≥7.5 mg/dL to <9.0 mg/dL: 1200-1600 mg 3 times/day, ≥9.0 mg/dL: 1600 mg 3 times/day. Maintenance dose adjustment based on serum phosphorous concentration (goal range of 3.5-5.5 mg/dL; maximum dose studied was equivalent to 13 g/day [sevelamer hydrochloride] or 14 g/day [sevelamer carbonate]): >5.5 mg/dL: Increase by 400-800 mg per meal at 2-week intervals, 3.5-5.5 mg/dL: Maintain current dose, <3.5 mg/dL: Decrease by 400-800 mg per meal.
STORAGE:
Store at room temperature not exceeding 30ᵒC.
DISCLAIMER:
This information is for the medical professionals & registered medical practitioners only. This product must be consumed with the valid prescription of registered medical practitioners.*Images/Pack are for representation purpose only.
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