DAPIZO 10

DAPIZO 10

Sodium-glucose cotransporter 2 (SGLT2), expressed in the proximal renal tubules, is responsible for the majority of the reabsorption of filtered glucose from the tubular lumen. Dapagliflozin is an inhibitor of SGLT2. By inhibiting SGLT2, dapagliflozin reduces reabsorption of filtered glucose and thereby promotes urinary glucose excretion

COMPOSITION

Dapagliflozin 10mg Tablets

MODE OF ACTION

Dapagliflozin is in a class of medications called Sodium-Glucose Cotransporter-2 (SGLT2) inhibitors. Dapagliflozin inhibits the Sodium-Glucose Cotransporter-2 (SGLT2) which is primarily located in the proximal tubule of the nephron.

SGLT2 facilitates 90% of glucose resorption in the kidneys and so its inhibition allows for glucose to be excreted in the urine. This excretion allows for better glycemic control and potentially weight loss in patients with type 2 diabetes mellitus.

INDICATION

  • In patients with CKD at risk of progression
  • In Diabetes Mellitus
  • In Heart Failure

DOSAGE

1 tablet once a day

STORAGE

Store at room temperature not exceeding 30ᵒC.

DISCLAIMER: This information is for the medical professionals & registered medical practitioners only. This product must be consumed with the valid prescription of registered medical practitioners.*Images/Pack are for representation purpose only.

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