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ERYNEX

ERYNEX

ERYNEX is recombinant human erythropoietin alpha (rHuEPO). Erythropoietin is a glycoprotein, which stimulates red blood cell (Erythropoiesis) production. It is produced in the kidney and stimulates the division and differentiation of committed erythroid progenitors in the bone marrow. Erythropoietin stimulates erythropoiesis in anemic patients with chronic renal failure in whom the endogenous production of erythropoietin is impaired.

COMPOSITION

Pre-filled syringes of Recombinant Human Erythropoietin Alpha Inj. (4000 IU/Ml and 10000 IU/mL)

MODE OF ACTION

Recombinant human erythropoietin; stimulates erythropoiesis via division and differentiation of progenitor cells in bone marrow.

INDICATION

Indicated in adult and paediatric patients for the:

    • Treatment of anemia due to Chronic Kidney Disease (CKD) in patients on dialysis and not on dialysis.
    • Treatment of anemia due to zidovudine in patients with HIV-infection.
    • Treatment of anemia due to the effects of concomitant myelosuppressive chemotherapy, and upon initiation, there is a minimum of two additional months of planned chemotherapy.
    • Reduction of allogeneic RBC transfusions in patients undergoing elective, noncardiac, nonvascular surgery.

DOSAGE

In patients with CKD

Adults: Initial dose of 50 to 100 Units/kg 3 times weekly

Pediatric: 50 Units/kg 3 times weekly

Individualize maintenance dose. Intravenous route recommended for patients on hemodialysis.

STORAGE

2ᵒC to 8ᵒC, should not be freeze

DISCLAIMER: This information is for the medical professionals & registered medical practitioners only. This product must be consumed with the valid prescription of registered medical practitioners.*Images/Pack are for representation purpose only.

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